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D

demerssy

@demerssy
Manufacturer
PAAB Notice
The responses, guidance, and advisories provided by the Pharmaceutical Advertising Advisory Board (PAAB), including but not limited to those available through the PAAB Forum, the PAAB website, and any PAAB correspondences, are specifically intended to assist individuals navigating the PAAB preclearance system. Repurposing or reproducing this content without written consent from the PAAB Commissioner is strictly prohibited. This prohibition includes, but is not limited to, use in machine learning or AI models.
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Recent Best Controversial

  • Guidance Regarding Duration of Clinical Trials Used as Reference Support in Advertising
    D demerssy

    @admin
    Hi, we would like to get some clarity on the type of studies that this guidance document encompasses, specifically for:
    • Extension study of pivotal trials that have a longer duration of follow-up than the one mentioned in the product monograph. In this case, the duration of use (# of cycles or # of years) of the drug is as per the recommended duration in the product monograph but the median follow-up is longer than the median follow-up mentioned in the product monograph, which include information on the primary and secondary outcomes data.
    • Further, the extension study is published in a peer-review journal and was a pre-planned extension or subsequent interim/final analyses of randomized, controlled trials (RCTs).

    With the appropriate balance and disclosures, would the above study be considered as reference support for advertising messages ?

    Thank you in advance for your response.

    Guidance on Code Application
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